三磷酸腺苷結(jié)合轉(zhuǎn)運(yùn)蛋白G超家族成員2重組兔單抗

Name: 三磷酸腺苷結(jié)合轉(zhuǎn)運(yùn)蛋白G超家族成員2重組兔單抗bsm-52821R
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簡(jiǎn)要描述：An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodami